severe burn is also known as third degree burn.This means more than 10% total body surface area, as well as loss of skin to depth of dermis.There is increased protein loss as albumin, and globulin,both blood proteins essential for wound healing as well as immunity and transport of substances across places in the body, as well as water, unless the burnt area of skin is closed by surgery and rehabilitation.Infection and increased loss from the burnt area occasions excessive loss not matched by increase in production.This poses a risk to the liver since it will be producing under heavy strain and reduced albumin alos means delayed wound healing as well as further reduction in protein production and a vicious cycle ensues.
