Science Why oxygen is necessary for mitochondrial ATP formation? Asked by Dr. John Carmen 12 years ago 1/20/2013 3:43 AM Last updated by anonymous 12 years ago 1/22/2013 12:37 AM
No it is not necessary, although it can happen. Technically, Glycolysis doesn't need oxygen to produce ATP. However, having said that, the products of glycolysis CAN go into the oxidative cycle,