Ozone layer
What chemicals are the major causes of ozone depletion in the stratosphere?
Prentice Hall Science Explorer - chapter 4

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Prentice Hall Science Explorer - chapter 4
chlorofluorocarbons (CFCs), hydrochlorofluorcarbons (HCFCs), carbon tetrachloride and methyl chloroform
Halons are the worst offenders because they are exponentially more caustic in nature than the other substances.