Chromosome what is the difference between sister chromatids and homologous chromosomes? Asked by bookragstutor 13 years ago 8/20/2012 9:52 AM Last updated by anonymous 13 years ago 12/3/2012 10:27 PM
Homologous chromosomes are those chromosomes that are paired up and are alike. Sister Chromatids are duplicate chromosomes attached to it's own copy(the original it came from).