Romance is a huge issue with teenagers and this book taps right into it. Blair is determined to lose her virginity during her senior year. She wants to have sex with Nate. She is constantly trying to get his attention and plan a special time with him, but he doesn't feel the same connection. Blair had discovered that he and Serena had sex previously, and this ruined her friendship with Serena. It also kept her jealous and suspicious throughout this book.