Who is Catherine of Aragon from The Wives of Henry VIII and what is their importance?

Catherine of Aragon arrived in England as Arthur's bride. She remained in England after Arthur's death, and Henry married her immediately after the death of his father, Henry VII. For nearly twenty years, Catherine served as the Queen of England, once took control during a crisis while her husband was out of the country. Catherine gave birth multiple times, twice to sons, but all save one of Catherine's children would die. When Henry VIII told Catherine that he wanted a divorce, she refused to deny that their marriage was sanctioned by God or that her marriage to Arthur was ever consummated. She insisted that Henry VIII knew she was a maiden on their wedding day. In the end, Catherine would live out her life in seclusion, dying of cancer.