Therese is seventeen-years-old, the oldest among the Lisbon sisters. She is perceived by the narrators as being a little awkward when compared the other girls in the Lisbon family. She is nerdish and not very handsome. According to the boys, she has a heavy face with the cheeks and eyes of a cow. Her physical abilities are also quite limited by her "two left feet." She is a good performer in school and she is mostly interested in science. She uses a ham radio to communicate with the outside world after the lockdown, but the mundane conversations that the narrators managed to intercept reveal nothing meaningful about the situation in the house or the possible motives for the foreshadowed suicides.