Uncle Enzo is the head of the Nova Sicilia organization, commonly known as The Mafia. Nova Sicilia owns the Cosa Nostra Pizza company, which employs Hiro at the beginning of the book. Uncle Enzo takes an interest in Y.T. after she delivers Hiro's pizza before its timer goes off. Uncle Enzo likes Y.T. because she can think for herself. Uncle Enzo fought in Vietnam, and he has a very practical approach with dealing with people. Uncle Enzo takes pride in small details, such as purchasing a new skateboard for Y.T. after Y.T. was kidnapped at the Fed building.