Portnoy's Complaint
Who is Anne McCaffery from Portnoy's Complaint and what is their importance?

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Anne is a non-Jewish shikse colleague of Alex's father who comes to dinner one night for a real "Jewish" meal. Alex wonders whether the mousey Anne and his father were having an affair, a suspicion that his mother (given her angry reaction to Anne's presence) evidently shared. The question is never explicitly answered.