Of Mice and Men

Frequently in Chapter 3, George plays Solitaire, a card game that requires only one player. What then, does Solitaire most likely symbolize

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One of the major themes of the book is the sense of isolation that all the men feel. Despite being around other men, there is a constant sense of loneliness and lack of intimacy. The game solitaire represents isolation. It is a one-person game. Men play it alone.