What is the main conflict in Madame Curie by Marie Curie?

Madame Curie: A Biography details the struggles and triumphs of one of the most famous scientists in the world. Marie's daughter Eve, the younger of the Curies' two children, wrote the biography clearly in reverence to her physicist mother. An artist and musician, Eve recreates moments from her mother's life in lyrically written scenes transposed with Marie's letters and journal entries, painting a vivid picture of the world-renowned physicist's personal and professional life.