What is the importance of the house at Henley Street in Stratford, Warwickshire in the novel, Hamnet?

A significant portion of the novel takes place at the house at Henley Street in Stratford, Warwickshire. This is the family home where the father grew up and where Hamnet, his sisters, his mother, and his grandparents live before the twins become ill. The house is in town and contains a separate unit alongside it where the father and Agnes made their own home separately from John and Mary after their nuptials. Following Hamnet’s death, the grandparents remain at the Henley Street house, but Agnes and her daughters move to a new house the father purchases for a fresh start.