Pain and Suffering is a recurring idea in the story. The concepts of pain and suffering play significant roles in the book, underscoring the price of addiction. James arrives at the clinic in terrible physical condition because he is an addict. He then suffers severe physical pain because of his addictions and the detoxification process. Detox involves vomiting, shaking, fatigue, hallucinations, panic, and user dreams, which make the recovering addict relive the feelings of using drugs. James also has other physical problems when he arrives, including four broken teeth, a broken nose, and a wound in his cheek. He undergoes extensive oral surgery and reconstruction.